Gayatri Annapareddy

Conducted exhaustive research on molecular docking, rigorously comparing docking results for 28 PDB IDs sourced from the Protein Data Bank using the Schrodinger and YASARA software. Engaged with the AMBER software for conducting molecular dynamics simulations for 30 PDB IDs, subsequently documenting and presenting results comprehensively in documents. Utilized ChemDraw for accurate and professional molecular structure drawings, displaying a meticulous approach to visual representation in chemical research.

Developed and maintained protocol for dNTPs preparation ensuring >99% purity, consistency, and quality throughout process. Collaborated with professors for synthesis dNTPs (dATP, dCTP, dGTP) synthesis, raising yield 20%, ensuring light-sensitive coverage, and cutting photodegradation 50% for product preservation. Monitored reversed-phase chromatography and mass spectrometry, ensuring precise data collection and analysis alignment with research objectives, resulting in a 11% increase in resolution.

Collaborated with the Head of the Documentation Department, Monitored HPLC, and Mass Spec with team members. Learned operation and maintenance of laboratory equipment, including pH meter, vortexes, centrifugation, and nitrogen evaporator, resulting in a 25% increase in equipment uptime. Implemented streamlined documentation processes, resulting in a 20% reduction in errors. Acquired extensive knowledge in documentation practices for instruments, ensuring accurate record-keeping.

Performed literature survey for project, concentrating on TLC, Column Chromatography techniques and achieved 20% faster reaction time through applied insights. Cultivated hands-on proficiency in techniques such as TLC monitoring for reaction progress and separation method column chromatography. Analyzed reaction components in UV spectroscopy after TLC, ensuring up to 80% precise data collection. Executed distillation under reduced pressure using a rotary evaporator resulted in a reduction of 14% in distillation time, highlighting adeptness in instrumental techniques.